{
  "$schema": "./schema.json",
  "dataset": {
    "name": "DNA Synthesis Provider Screening Disclosure Tracker",
    "version": "0.2.0",
    "description": "Public-disclosure status of biosecurity screening policies at commercial DNA and gene synthesis providers worldwide. Documents what each provider publicly states, not what it does.",
    "license": "CC-BY-4.0",
    "maintainer": "Mohith Kodavati",
    "last_updated": "2026-08-07",
    "update_cadence": "monthly",
    "coverage_note": "Provider list is a seed set of major commercial synthesis and oligo suppliers. Cells marked 'unverified' have not yet been read against a primary source and are not findings.",
    "sources": {
      "igsc_member": {
        "name": "International Gene Synthesis Consortium member roster",
        "url": "https://genesynthesisconsortium.org/",
        "retrieved": "2026-08-07",
        "note": "41 member organisations listed. 'no' means the provider does not appear on that published roster; it is not a statement about the provider's practices."
      },
      "legal_mandate_in_jurisdiction": {
        "name": "OSTP/NSTC Framework for Nucleic Acid Synthesis Screening (April 2024)",
        "url": "https://aspr.hhs.gov/S3/Documents/OSTP-Nucleic-Acid-Synthesis-Screening-Framework-Sep2024.pdf",
        "retrieved": "2026-08-07",
        "note": "The US framework operates as a procurement condition: federally funded purchasers must buy from providers that self-attest. It imposes no direct statutory duty on providers, and no penalty attaches to a provider that never attests. Recorded as 'partial' for the United States for that reason. Non-US jurisdictions are not yet researched."
      }
    }
  },
  "providers": [
    {
      "id": "twist-bioscience",
      "name": "Twist Bioscience",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "yes",
      "screens_sequences": "stated",
      "screens_customers": "stated",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://www.twistbioscience.com/blog/perspectives/supporting-responsible-research-through-comprehensive-biosecurity",
      "source_note": "Biosecurity article, 'Screening of Sequences and Customers' section ('screens all double-stranded DNA sequences ordered'; customers screened against government lists) and 'National and International Regulations' section (cites the US Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA).",
      "last_verified": "2026-08-07"
    },
    {
      "id": "idt",
      "name": "Integrated DNA Technologies (IDT)",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "yes",
      "screens_sequences": "stated",
      "screens_customers": "stated",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://www.idtdna.com/page/support-and-education/decoded-plus/idt-s-commitment-to-biosecurity",
      "source_note": "'Our Commitment to Biosecurity Measures' page: screens the sequence of every gene and gene fragment order and verifies that customers are legitimate scientists; states it follows the 2010 US Screening Framework Guidance. NOTE: direct fetch redirect-looped; page text retrieved via search index. Re-read in a browser to confirm wording.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "thermo-fisher-geneart",
      "name": "Thermo Fisher Scientific (GeneArt)",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "yes",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": null,
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "azenta-genewiz",
      "name": "Azenta Life Sciences (GENEWIZ)",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "yes",
      "screens_sequences": "stated",
      "screens_customers": "stated",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://www.genewiz.com/public/services/gene-synthesis/gene-synthesis-service",
      "source_note": "'Biosecurity' heading: 'thorough screening of both ordered gene sequences to identify any sequences of concern (SOCs) and the customers submitting those orders'; cites the OSTP Framework for Nucleic Acid Synthesis Screening of 29 April 2024.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "aldevron",
      "name": "Aldevron",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "yes",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": null,
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "ansa-biotechnologies",
      "name": "Ansa Biotechnologies",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "yes",
      "screens_sequences": "stated",
      "screens_customers": "not_stated",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://ansabio.com/resources/frequently-asked-questions/",
      "source_note": "FAQ, 'How does Ansa address Biosecurity?': 'All requested sequences are screened according to the NSTC Framework For Nucleic Acid Synthesis Screening before being synthesized' and IGSC Harmonized Screening Protocol adherence. The page describes sequence screening only — no customer-screening claim appears.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "telesis-bio",
      "name": "Telesis Bio",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "yes",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://files.telesisbio.com/docs/46167_TELESIS_BIO_INC_GENERAL_TERMS_AND_CONDITIONS_OF_SALE_20OCT2023.pdf",
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "atum",
      "name": "ATUM",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "yes",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://www.atum.bio/our-commitments/",
      "source_note": "'Our Commitments' page: 'ATUM self-attests to complying with the US Framework for Nucleic Acid Synthesis Screening' and notes federally funded entities rely on the attestation. NOTE: direct fetch returned 404 (likely bot filtering); text retrieved via search index. Re-read in a browser before relying on the sequence/customer cells.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "bio-synthesis",
      "name": "Bio-Synthesis Inc.",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://www.biosyn.com/faq/Does-Biosynthesis-adhere-to-the-guidelines-outlined-by-the-US-Department-of-Health-and-Human-Resources-in-the-US-Framework-for-Nucleic-Acid-Synthesis-Screening.aspx",
      "source_note": "Dedicated FAQ page titled 'Does Biosynthesis adhere to the guidelines outlined by the US Department of Health and Human Resources in the US Framework for Nucleic Acid Synthesis Screening' — answered affirmatively. Sequence/customer specifics not separately verified.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "gene-universal",
      "name": "Gene Universal",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://www.geneuniversal.com/about-us/our-commitment",
      "source_note": "'Our Commitment' page: 'Gene Universal self-attests to its compliance with the US Framework for Nucleic Acid Synthesis Screening', noting federally funded entities rely on the attestation.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "vectorbuilder",
      "name": "VectorBuilder",
      "hq_country": "United States",
      "hq_region": "North America",
      "igsc_member": "no",
      "screens_sequences": "not_stated",
      "screens_customers": "not_stated",
      "cites_us_framework": "not_stated",
      "legal_mandate_in_jurisdiction": "partial",
      "policy_url": "https://en.vectorbuilder.com/support/legal-statement/biosafety.html",
      "source_note": "Biosafety legal statement. The page places obligations on the CUSTOMER (customer confirms materials are not pathogenic/infectious/toxic and that research complies with law) and describes no screening performed by VectorBuilder. No sequence-screening claim, no customer-verification claim, and no reference to the HHS or OSTP frameworks appear on the page.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "biomatik",
      "name": "Biomatik",
      "hq_country": "Canada",
      "hq_region": "North America",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": "https://www.biomatik.com/content/service_docs/Self%20Attestation_BM_20240909.pdf",
      "source_note": "Self-attestation PDF hosted on biomatik.com, titled 'White House Nucleic Acid Synthesis Screening Framework' self-attestation, dated 2024-09-09. Document exists and is published by the provider; its text was not machine-readable, so sequence/customer cells remain unverified pending a manual read.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "bio-basic",
      "name": "Bio Basic Inc.",
      "hq_country": "Canada",
      "hq_region": "North America",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": "https://www.biobasic.com/gene-synthesis",
      "source_note": "Gene synthesis service page: 'Bio Basic Inc. self-attests to complying with the US Framework for Nucleic Acid Synthesis Screening.'",
      "last_verified": "2026-08-07"
    },
    {
      "id": "eurofins-genomics",
      "name": "Eurofins Genomics",
      "hq_country": "Germany",
      "hq_region": "Europe",
      "igsc_member": "no",
      "screens_sequences": "stated",
      "screens_customers": "stated",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": "https://eurofinsgenomics.com/en/about-us/about-us/us-framework-for-nucleic-acid-synthesis-screening-compliance/",
      "source_note": "Dedicated 'US Framework for Nucleic Acid Synthesis Screening' compliance page: 'Eurofins Genomics self-attests to complying with the framework for nucleic acid synthesis screening', where the attested framework covers 'screening sequences for sequences of concern (SOCs), screening customers which try to order SOCs'. Page also notes the screening threshold drops from 200 to 50 bases in October 2026.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "biocat",
      "name": "BioCat GmbH",
      "hq_country": "Germany",
      "hq_region": "Europe",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": null,
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "kaneka-eurogentec",
      "name": "Kaneka Eurogentec",
      "hq_country": "Belgium",
      "hq_region": "Europe",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": null,
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "proteogenix",
      "name": "ProteoGenix",
      "hq_country": "France",
      "hq_region": "Europe",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": "https://www.proteogenix.science/custom-gene-synthesis/",
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "genscript",
      "name": "GenScript Biotech",
      "hq_country": "China",
      "hq_region": "Asia-Pacific",
      "igsc_member": "yes",
      "screens_sequences": "stated",
      "screens_customers": "stated",
      "cites_us_framework": "stated",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": "https://www.genscript.com/gsfiles/techfiles/Framework_for_Nucleic_Acid_Synthesis_Screening_Formal_Statement_from_GenScript.pdf",
      "source_note": "Formal self-attestation PDF dated 2024-10-10: 'GenScript screens synthetic DNA orders for sequences of concern and conducts customer due diligence', made with reference to the US nucleic acid synthesis screening framework.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "synbio-technologies",
      "name": "Synbio Technologies",
      "hq_country": "China",
      "hq_region": "Asia-Pacific",
      "igsc_member": "yes",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": "https://synbio-tech.com/gene-synthesis",
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "sangon-biotech",
      "name": "Sangon Biotech",
      "hq_country": "China",
      "hq_region": "Asia-Pacific",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": null,
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "tsingke",
      "name": "Tsingke Biotechnology",
      "hq_country": "China",
      "hq_region": "Asia-Pacific",
      "igsc_member": "yes",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": null,
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "molecular-cloud",
      "name": "Molecular Cloud",
      "hq_country": "China",
      "hq_region": "Asia-Pacific",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": null,
      "source_note": null,
      "last_verified": null
    },
    {
      "id": "bioneer",
      "name": "Bioneer Corporation",
      "hq_country": "South Korea",
      "hq_region": "Asia-Pacific",
      "igsc_member": "yes",
      "screens_sequences": "stated",
      "screens_customers": "stated",
      "cites_us_framework": "not_stated",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": "https://eng.bioneer.com/gene-synthesis-gene-synthesis-customorder.html",
      "source_note": "Gene synthesis order page, 'What are potentially hazardous gene sequences and why is strict verification necessary?': 'As a responsible provider adhering to the IGSC Harmonized Screening Protocol, Bioneer rigorously verifies all orders'; customer verification 'to confirm that the order is placed by a legitimate institution'. Cites the IGSC Harmonized Screening Protocol; no reference to the HHS or OSTP US frameworks appears on the page.",
      "last_verified": "2026-08-07"
    },
    {
      "id": "macrogen",
      "name": "Macrogen",
      "hq_country": "South Korea",
      "hq_region": "Asia-Pacific",
      "igsc_member": "no",
      "screens_sequences": "unverified",
      "screens_customers": "unverified",
      "cites_us_framework": "unverified",
      "legal_mandate_in_jurisdiction": "unverified",
      "policy_url": "https://www.macrogen.com/en/business/research/gene-synthesis",
      "source_note": null,
      "last_verified": null
    }
  ]
}
